Nutramax Laboratories Denamarin Liver Health Supplement for Small Dogs and Cats - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

Okay, so my cat is ten and suddenly his liver levels were bad but nothing else. My other 3 cats all got healthy bloodwork. We’re not sure what’s wrong but we’re working on the liver levels first to see if once they’re fully down, maybe they’ll stay that way. I asked my vet about Denamarin based on my research. He said great idea (why I’m the one who thought of it is a whole separate issue I’m tired of vets man.) After about six weeks his liver levels went down 60 points. So he went from 589 to 529. Other areas of his bloodwork that weren’t perfect and not related to the liver somehow also improved. other improvements: his ears have always had coffee grind black stuff likely from constant yeast or allergies, now that’s gone, he gained weight very drastically and was losing weight before even though he was eating so much, he’s calm (and he’s an anxious out of control bengal) and sleeps better.Now, the vets, instructions and Google all told me there were specific ways to give this pill and it would ONLY work if I did it this way:No cutting up or crushing, empty stomach, don’t give with food, and dont feed until one hour after the pill is taken.Well. The second I saw the pill, the big, blue round pill I instantly gave up. I tried to do it their way. It didn’t work.I did it my way and it worked:1) yes to the empty stomach (sometimes I’d feed him at 4/5 am to stop his early morning wake up then gave the pill a few hours later so it wasn’t always a total empty stomach but many times it was)2) i cut it up. It says not to cut or crush. I cut the pill with a flat blade kitchen knife into pieces smaller than his teeth.3) I soak a bunch of Stella Chewys duck freeze dried treats until they got very soft and I would put one piece into a molded up piece of treat. So he’d end up with about ten pieces of molded wet treat with a piece of pill inside each one. Many times he eats it fine. Sometimes he’ll turn away. I will sometimes add purina probiotics sprinkles on top and it helps. There are some days once in a blue moon where he will absolutely just not be eat the treats but 85% of the time he will be eat it.And doing it my way, not according to the rules that are impossible to follow for a cat, still worked. His levels are going down pretty quickly.Just wanted to share my process bc it works. I told my vet and he said to keep doing it the way I’m doing it.However if you try this and the levels don’t change then this might not be the best process for you.Anyway 5 stars. This stuff works. The pill size and smell of it sucks for cats.

I have 2 cats which I adopted in 2010 that spent the first 3.5 years of their life with chronic diarrhea, on and off metronidazole during that time, only for the diarrhea to return shortly after the antibiotic was stopped. Stools were always negative, but I found out my one cat had sky-high liver enzymes. I tried this (one pill for each cat at bedtime) and they had perfect poop within about 2 days. Also, my cat's liver enzymes quickly returned to normal.I treated the cat with the high liver enzymes for about 3 months and stopped. Both cats still had perfect poop, but the cat who had the sky-high liver enzymes in the past (at some point) started hiding under a comforter on the chair all day (which was not like him), and when I'd peek under I could just tell he wasn't feeling well. I didn't take him to the vet because he'd always act perky at mealtime. (In retrospect, I believe he started hiding around the time I stopped the Denamarin.)Fast forward to now, 2016...My husband & I started giving them bits of table food because we couldn't resist their begging - perhaps the trigger? Both cats developed diarrhea again and were treated by a new vet with metronidazole & amoxicillin (both positive for clostridium). Looking back in their records, they were positive for this in the past, but vets only ever treated them with metronidazole and never mentioned anything about clostridium to me. I was hopeful that clostridium had been been the cause all along and that these 2 antibiotics together would finally rid them of diarrhea forever, but even after a round of this combination, they still had stools the consistency of pudding. When I asked for another round of antibiotics, the vet refused and told me to take them both to a specialist and recommended (VERY expensive) endoscopies. I had already spent so much money in the past on stool tests, even a comprehensive and expensive stool test, probiotics, digestive enzymes, various cat foods, etc... Nothing ever helped.So I decided to start them both on Denamarin again - one pill at bedtime for each - and their stools were perfect again within 2 days.This stuff is nothing short of a MIRACLE for cats with CHRONIC DIARRHEA. I've therefore decided I will be giving them this f-o-r-e-v-e-r, and of course, resist giving them any table food. :-/+++++UPDATE (November 2017)...additional information...This is nothing short of a miracle for acute and chronic diarrhea in cats. I have two cats who had acute and chronic diarrhea from the day I brought them home from a shelter as kittens. THREE & A HALF YEARS of stool testing, even an expensive 'comprehensive stool panel' on the one who always got the sickest, all negative except a toxin present for clostridium perfringens, which the vet blew off as 'harmless' and not the cause. Both cats would always be prescribed a course of Metronidazole, so I knew a 'bug' was involved. Metronidazole would help firm them up some in the sickest cat, completely in the other cat, but then back to the mashed potato poop and squirts in no time. Whether or not it was this 'harmless' bacteria or not, I have no idea. I was told it must be 'food allergies', but tried every limited ingredient canned cat food I could find to no avail. And BOTH cats supposedly had food allergies even after stopping the tidbits of table food?My one cat, when tested, had high liver enzymes, 5 times higher than normal. I spent many nights googling how to bring his liver enzymes down. That is how I first came across Denamarin. He honestly looked like he was dying. ONE PILL and within the next day or two he had his FIRST normal bowel movement in his LIFE. I can't believe he had to live the first 3 1/2 years of his life sick like this. He was the one who would always get the sickest, but eventually if one had diarrhea, the other one would get it too. I will give him one pill for the rest of his life because when I stop, within a couple of months he'll start look sickly and eventually have an acute bout of diarrhea, turning chronic, the other cat contracting it soon after.During the time period I had stopped giving this one cat Denamarin, he developed one of these horrible bouts of diarrhea (the other cat soon after). He wouldn't eat, would pace and pant until he threw up to the point of dehydration, and would run to the litter box with the squirts, runs, mushy poop. Took him to an emergency veterinary hospital, and all they gave him was an anti-nausea medication, something to calm his stomach, and sub-q fluids. Next day he had diarrhea still. I called the hospital, and this vet refused to prescribe Metronidazole even though I'd just paid $530. So I pulled out the Denamarin...diarrhea gone the next day.Just last night I noticed the other cat had formed, but soft stool, mushy at the very end. I panicked and gave him a Denamarin. He didn't poop at all today.Denamarin is a MIRACLE, and if you have a cat in this situation...chronic or acute diarrhea, routine stool tests negative or comprehensive stool panels positive for ANY so-called 'harmless' bacteria or bacterial toxin, this is worth a try. Seriously, I love this stuff so much, I could do a commercial for it. I'm posting this, not because I'm positive it will help every cat, but I plead with anyone in similar situations to give this a try. I am convinced this pill saved my one cat's life. I give it to him daily, and I watch the stools of my other cat and may even start giving it to him daily as a precaution.

SOMETHING in my initial review didn't meet Amazon's "standards", so I'm rewriting. This seems to help my cat. I'm lucky that my cat is easy to pill. Since I've been using it, his blood functions have improved. Good stuff.

Easy to open and nice size- easy to poke into some soft dog food n for dog to swallow.

My cat is better so I don’t want to order this item more

Helpful to my Dog! Price is much better than Vet.

With the “new beige” pill my cat started to vomiting. Threre is anyway to get the blue pill again somewhere?